Updated December 2025

Best Information Systems Programs in Missouri: Top Schools & Colleges Ranked

Ranking 20 top accredited information systems programs in Missouri. Compare schools by tuition, graduation rates, and career outcomes in Kansas City, St. Louis.

Programs Ranked:20
Median Salary:$104,000
Cost of Living:90.8%
Tech Hubs:2

Top 3 Information Systems Programs in Missouri 2025

๐Ÿฅ‡ #1

Washington University in St Louis

Saint Louis, MOPrivate

71 information systems graduates annually, 97% graduation rate

$62K
Tuition/yr
97%
Grad Rate
76.8
Score
๐Ÿฅˆ #2

University of Central Missouri

Warrensburg, MOPublic

300 information systems graduates annually, N/A% graduation rate

$8K
Tuition/yr
71.4
Score
๐Ÿฅ‰ #3

University of Missouri-Columbia

Columbia, MOPublic

88 information systems graduates annually, 80% graduation rate

$13K
Tuition/yr
80%
Grad Rate
60.8
Score
Key Takeaways
  • 1.Missouri offers 20+ accredited information systems programs across public and private universities
  • 2.Washington University in St Louis leads with 97% graduation rate
  • 3.Missouri software developers earn median $104,000 annually (BLS OES 2024)
  • 4.Tech opportunities concentrated in Kansas City, St. Louis
  • 5.Cost of living index: 90.8% of US average (below average)

Information Systems Education in Missouri: Overview

Missouri offers 20 accredited information systems programs, producing approximately 824 graduates annually. The state's tech industry is centered in Kansas City, St. Louis, with major employers including Cerner, World Wide Technology, Bayer.

With a median software developer salary of $104,000 (BLS OES May 2024) and a cost of living index of 90.8% compared to the US average, Missouri offers above-average purchasing power for tech workers compared to higher-cost coastal markets.

The top information systems programs in the state are led by Washington University in St Louis, University of Central Missouri, University of Missouri-Columbia, each offering distinct advantages in terms of program size, graduation rates, and industry connections.

Ranking Methodology

Based on 20 programs from IPEDS 2023, BLS OES May 2024

Program Strength35%

Information Systems degree completions indicating program size, faculty, and resources (IPEDS 2023)

Graduation Rate25%

6-year completion rate from IPEDS 2023

Selectivity20%

Admission rate from IPEDS 2023 (lower = more selective)

Career Outcomes20%

Missouri-specific salaries from BLS OES May 2024

Missouri Information Systems Programs Rankings 2025

Rank
1Washington University in St LouisSaint Louis, MOPrivate$61,75097%76.8
2University of Central MissouriWarrensburg, MOPublic$8,325โ€”71.4
3University of Missouri-ColumbiaColumbia, MOPublic$13,00880%60.8
4Saint Louis UniversitySaint Louis, MOPrivate$52,26092%58.6
5Missouri State University-SpringfieldSpringfield, MOPublic$7,812โ€”51.6
6University of Missouri-Kansas CityKansas City, MOPublic$11,19098%51.6
7Park UniversityParkville, MOPrivate$11,908โ€”49.7
8Columbia CollegeColumbia, MOPrivate$12,268โ€”49.5
9University of Missouri-St LouisSaint Louis, MOPublic$14,400โ€”46.6
10College of the OzarksPoint Lookout, MOPrivate$20,800โ€”45.8
11Missouri University of Science and TechnologyRolla, MOPublic$13,008โ€”44
12Maryville University of Saint LouisSaint Louis, MOPrivate$24,76686%43.1
13Lindenwood UniversitySaint Charles, MOPrivate$19,900โ€”40.3
14Lincoln UniversityJefferson City, MOPublic$7,370โ€”39.6
15Missouri Baptist UniversitySaint Louis, MOPrivate$31,530โ€”38.9
16Missouri Western State UniversitySaint Joseph, MOPublic$7,740โ€”38.8
17Northwest Missouri State UniversityMaryville, MOPublic$6,442โ€”33.6
18Culver-Stockton CollegeCanton, MOPrivate$29,420โ€”32.5
19Central Methodist University-College of Liberal Arts and SciencesFayette, MOPrivate$26,360โ€”31.2
20Central Methodist University-College of Graduate and Extended StudiesFayette, MOPrivate$6,4806%22.9

Top 5 Information Systems Programs in Missouri: Side-by-Side

SchoolWashUU of Central MissouriU of Missouri-ColumbiaSaint LouisMissouri State University...
Rank
#1
#2
#3
#4
#5
In-State Tuition
$61,750
$8,325
$13,008
$52,260
$7,812
Graduation Rate
97%
N/A%
80%
92%
N/A%
Annual Graduates
71
300
88
53
104
Acceptance Rate
12%
69%
77%
81%
91%
Type
Private
Public
Public
Private
Public
Score
76.8/100
71.4/100
60.8/100
58.6/100
51.6/100

Best Bachelor's Degree Programs in Information Systems in Missouri

Missouri offers 19 bachelor's-level information systems programs. The top schools for undergraduate study are University of Missouri-Columbia, Washington University in St Louis, Missouri State University-Springfield. These programs prepare students for entry-level positions paying approximately $72,800 in the Missouri market.

A bachelor's in information systems typically requires 120-128 credit hours and takes 4 years to complete. For national rankings, see our Best Information Systems Bachelor's Programs guide.

Top 3 Information Systems Bachelor's Programs in Missouri

SchoolTuitionGrad RateGraduatesScore
#1 U of Missouri-Columbia
$13,008
80%
88
60.8
#2 WashU
$61,750
97%
25
73.3
#3 Missouri State University...
$7,812
N/A%
104
51.6

Top Information Systems Schools for Master's Degrees in Missouri

For graduate study, Missouri offers 8 master's-level information systems programs. Leading institutions include Washington University in St Louis, University of Central Missouri, Saint Louis University. A master's degree can boost earning potential by 15-25%, with senior roles in Missouri reaching $135,200 or more.

Top 3 Information Systems Master's Programs in Missouri

SchoolTuitionGrad RateGraduatesScore
#1 WashU
$61,750
97%
71
76.8
#2 U of Central Missouri
$8,325
N/A%
300
71.4
#3 Saint Louis
$52,260
92%
53
58.6

Most Affordable Information Systems Colleges in Missouri

For budget-conscious students, the most affordable information systems programs in Missouri are at Northwest Missouri State University ($6,442/year), Central Methodist University-College of Graduate and Extended Studies ($6,480/year), Lincoln University ($7,370/year). These programs offer strong ROI given Missouri's competitive tech salaries.

At Northwest Missouri State University, a 4-year degree costs approximately $25,768 in tuition alone. With entry-level salaries around $72,800, graduates can typically recoup their investment within 0.7 years. See our Most Affordable Information Systems Programs for national comparisons.

Most Affordable Information Systems Programs in Missouri (with ROI)

SchoolAnnual Tuition4-Year CostPayback PeriodType
#1 Northwest Missouri State
$6,442
$25,768
0.7 years
Public
#2 Central Methodist...
$6,480
$25,920
0.7 years
Private
#3 Lincoln
$7,370
$29,480
0.8 years
Public

Detailed Program Spotlights: Inside the Top 5 Information Systems Schools in Missouri

Below are detailed profiles of the top 5 information systems programs in Missouri, including admissions requirements, curriculum highlights, career outcomes, and what makes each program unique. Data sourced from official university websites and IPEDS 2023.

#11 Designation

Washington University in St Louis

Saint Louis, MO โ€ข Private

Delivery:On-Campus
Visit Program

Program Highlights

  • โ€ข Annual Tuition: $61,750 (in-state)
  • โ€ข Graduation Rate: 97% (IPEDS 2023)
  • โ€ข Information Systems Graduates: 71 annually
  • โ€ข Acceptance Rate: 12%
  • โ€ข Ranking Score: 76.8 / 100

Program Strengths

  • 97% graduation rate
  • 71 information systems graduates annually
  • Private institution
  • Overall score: 76.8 / 100

Why Ranked #1

Ranked #1 based on graduation rate (97%), program size (71 graduates), state salary outcomes ($104,000), and selectivity (12% acceptance rate). Data from IPEDS 2023 and BLS OES 2024.

Why Choose This Program

The MISM program combines managerial and technical acumen taught by leading professionals from the information systems industry, with courses designed with input from employers and thought leaders. The program is a STEM-qualified degree that builds both leadership competencies and technical capabilities for IT enterprise leadership.

Program Accreditations & Designations
STEM program
Available Scholarships
$100 percent graduate tuition coverage for qualified veterans through WashU McKelvey School of Engineering and VA
Program Details
  • Credits: 30 units (10 courses)
#2

University of Central Missouri

Warrensburg, MO โ€ข Public

Delivery:On-Campus

Program Highlights

  • โ€ข Annual Tuition: $8,325 (in-state)
  • โ€ข Graduation Rate: N/A% (IPEDS 2023)
  • โ€ข Information Systems Graduates: 300 annually
  • โ€ข Acceptance Rate: 69%
  • โ€ข Ranking Score: 71.4 / 100

Program Strengths

  • N/A% graduation rate
  • 300 information systems graduates annually
  • Public institution
  • Overall score: 71.4 / 100

Why Ranked #2

Ranked #2 based on graduation rate (N/A%), program size (300 graduates), state salary outcomes ($104,000), and selectivity (69% acceptance rate). Data from IPEDS 2023 and BLS OES 2024.

#3

University of Missouri-Columbia

Columbia, MO โ€ข Public

Delivery:On-Campus

Program Highlights

  • โ€ข Annual Tuition: $13,008 (in-state)
  • โ€ข Graduation Rate: 80% (IPEDS 2023)
  • โ€ข Information Systems Graduates: 88 annually
  • โ€ข Acceptance Rate: 77%
  • โ€ข Ranking Score: 60.8 / 100

Program Strengths

  • 80% graduation rate
  • 88 information systems graduates annually
  • Public institution
  • Overall score: 60.8 / 100

Why Ranked #3

Ranked #3 based on graduation rate (80%), program size (88 graduates), state salary outcomes ($104,000), and selectivity (77% acceptance rate). Data from IPEDS 2023 and BLS OES 2024.

#4

Saint Louis University

Saint Louis, MO โ€ข Private

Delivery:On-Campus
Visit Program

Program Highlights

  • โ€ข Annual Tuition: $52,260 (in-state)
  • โ€ข Graduation Rate: 92% (IPEDS 2023)
  • โ€ข Information Systems Graduates: 53 annually
  • โ€ข Acceptance Rate: 81%
  • โ€ข Ranking Score: 58.6 / 100

Program Strengths

  • 92% graduation rate
  • 53 information systems graduates annually
  • Private institution
  • Overall score: 58.6 / 100

Why Ranked #4

Ranked #4 based on graduation rate (92%), program size (53 graduates), state salary outcomes ($104,000), and selectivity (81% acceptance rate). Data from IPEDS 2023 and BLS OES 2024.

Why Choose This Program

The M.S. in Information Systems is a 33-credit program offering 100% online delivery with flexible eight-week terms for working professionals. Students gain skills in software development, analytics, evidence-based decision-making, ethics and leadership while learning from a diverse network of peers from around the world.

Admissions
  • Min GPA: 3.0
Program Details
  • Credits: 33 credits
#5

Missouri State University-Springfield

Springfield, MO โ€ข Public

Delivery:On-Campus

Program Highlights

  • โ€ข Annual Tuition: $7,812 (in-state)
  • โ€ข Graduation Rate: N/A% (IPEDS 2023)
  • โ€ข Information Systems Graduates: 104 annually
  • โ€ข Acceptance Rate: 91%
  • โ€ข Ranking Score: 51.6 / 100

Program Strengths

  • N/A% graduation rate
  • 104 information systems graduates annually
  • Public institution
  • Overall score: 51.6 / 100

Why Ranked #5

Ranked #5 based on graduation rate (N/A%), program size (104 graduates), state salary outcomes ($104,000), and selectivity (91% acceptance rate). Data from IPEDS 2023 and BLS OES 2024.

$72,800
Starting Salary
$104,000
Mid-Career
+17%
Job Growth
7,738
Annual Openings

Career Paths

+17%

Software Developer opportunities in Missouri with strong job growth.

Median Salary:$104,465

Data Scientist

SOC 15-2051
+35%

Data Scientist opportunities in Missouri with strong job growth.

Median Salary:$97,339

DevOps Engineer

SOC 15-1244
+22%

DevOps Engineer opportunities in Missouri with strong job growth.

Median Salary:$115,820

AI/ML Engineer

SOC 15-1299
+23%

AI/ML Engineer opportunities in Missouri with strong job growth.

Median Salary:$106,544
+33%

Cybersecurity Analyst opportunities in Missouri with strong job growth.

Median Salary:$121,212

Which Should You Choose?

Choose Missouri if...
  • You want access to tech jobs in Kansas City, St. Louis
  • You're seeking lower cost of living than coastal states (90.8% of US average)
  • You want to work at companies like Cerner or World Wide Technology
  • You prefer Missouri's quality of life
Consider other states if...
  • You prioritize highest possible salary (consider CA, WA, NY)
  • You want more program options (CA has 100+ vs Missouri's 20)
  • You're looking for major coastal tech hub concentration (consider SF, Seattle, NYC)

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Information Systems Programs in Other States

Information Systems in Missouri FAQ

Related Resources

Data Sources & Methodology

Integrated Postsecondary Education Data System - program completions, graduation rates, tuition, admissions

Bureau of Labor Statistics Occupational Employment and Wage Statistics - Missouri salary data

2023-2033 occupational outlook and growth projections

Official University Websites

Program-specific admissions, curriculum, and career outcome data

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